Successful pregnancy after operation in an infertile woman caused by luteinizing hormone-secreting pituitary adenoma: case report and literature review

Table 1 Cases of LH-secreting adenomas reported in the English literature

Study	Age	gender	Symptoms	Tumor	LH (mIU/mL)	a-subunit (ng/ml)	FSH (mIU/mL)	E2(pg/ml)	T (ng/ml)	Medical therapy	Operation
Peterso [2]	30	Male	azzospermic	Intrasellar mass	207 (6–26)	72(< 0.5–2.5)	2(normal range 5–25)	110(< 10–60)	1500 (300–1000)	TRH, LRH, L-dopa, metyrapone,	Transsphenoidal operation
Klibanski [3]	48	Male	Increase in libido, blind	Pituitary tumor	99 (2–18)	5.7(< 2.5)	5.5(−)	219(< 52)	1660 (300–1100)		Transfrontal craniotomy
Vos [4]	20	Male	Grand-mal seizures	Hypothalamic-pituitary tumor	140 (2–15)	9105 (3–30)	4 (3–12)		53 (12–30)	SMS201–995	Transsphenoidal operation
Castelo-Branco [5]	31	Female	OHSS	Pituitary macroadenoma	4.9(−)		7.2(−)			Prolactin, cabergoline, somatostatin	Transsphenoidal operation
Roman [6]	33	Male	Testicular pain, dysuria	Intrasellar mass	207 (3–9)	72(< 0.5–2.5)	2 (4–11)		15,000 (30000–80,000)	LHRH	Transsphenoidal operation
Kadakia [7]	9	Male	Precocious puberty	Anterior pituitary tumor	5(< 0.49)		< 0.05 (0.87–9.16)		44,200(< 4200)	leuprolide	Transsphenoidal operation

LH Luteinizing Hormone, FSH Follicle stimulating hormone, E2 estradiol, T Testosterone, SMS somatostatin, OHSS ovarian hyperstimulation syndrome

ISSN: 1472-6823